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Alpha BRAIN™ - 30 ct. Veggie Capsules

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The Flagship Complete Balanced Nootropic.

  • Razor Sharp Focus
  • Mental Drive
  • Lucid Dreams
Product Description:
  • 1 bottle of 30 Alpha BRAIN Veggie Capsules (1.6 oz)
ALPHA BRAIN is a world-class nootropic stack (read: mental supplement) containing a synergistic blend of eleven natural nutrients. This blend is designed to help you elevate levels of major neurotransmitters and actualize your mind's true potential.

The result for thousands of satisfied customers is an extraordinary combination of lucid dreams, mental focus, mental drive, and mental clarity.

ALPHA BRAIN helps to upgrade your life in three ways:

Remain Calm, Focused, and Mentally Driven

ALPHA BRAIN aims to decrease our levels of endogenous stress while providing the tools to handle demanding situations, allowing a clear and focused mind. The Phosphatidylserine in ALPHA BRAIN is a phospholipid cell component known to possess ergogenic properties and promote stress tolerance in high performance athletes.

Stress Reduction and Cognitive Enhancement

Prolonged stress will take down your mental abilities, strip your immunity, and blunt your competitive edge. Fortunately, ALPHA BRAIN intervenes with natural anti-stress compounds that mitigate the brain's stress responses and provide a profound calming effect.

Better Brain Health

A number of neurological conditionals and age-related challenges are linked to free radical damage. Alpha BRAIN provides the most beneficial antioxidants to quench and scavenge free radicals across the blood-brain barrier. Natural ingredients such as Pterostilbene (typically found in blueberries), Bacopa, and Vinpoecetine also help prevent free radical damage, provide antioxidant protection, exhibit anti-inflammatory properties, and increase blood flow to the brain.
Alpha BRAIN, the flagship cognitive enhancing supplement from Onnit Labs, contains a serving of nine natural, well-researched compounds to create an effective and balanced nootropic. Alpha BRAIN aims to elevate focus and mental clarity to help the brain achieve improved cognitive functioning. The ingredients in Alpha BRAIN are centered on three aspects of enhanced cognition: elevating levels of endogenous neurotransmitters, providing anti-stress compounds, and promoting long-term neuroprotection.
Suggested Use: For enhanced mental performance take a serving of 1-2 capsules in the morning or early afternoon, preferably with a light meal. Depending on body size and tolerance you may increase this to a maximum serving of 3 capsules. For enhanced dream state you may take a serving of 1-2 capsules 4-6 hours prior to sleep, preferably with a light meal. Do not exceed 4 capsules in a 24 hours period unless otherwise directed by a healthcare practitioner.

Warning: DO NOT use if pregnant, nursing, or under the age of 18. Consult with a healthcare practioner before taking this or any nutritional supplement if you have or suspect a medical condition, are taking any medications, particularly blood thinners or drugs designed to interact with neurotransmitters, over the counter products, or other non-Onnit dietary supplements. If you experience any adverse reaction form taking this product discontinue immediately and contact your health care practitioner. Do not use it if safety seal is broken or missing. Store in a cool dry place. KEEP OUT OF REACH OF CHILDREN.


Pyridoxine (Vitamin B6): One of the body's busiest vitamins, involved in an estimated 101 chemical reactions. One of its primary tasks is to aid in the manufacturing of amino acids and neurotransmitters. Some of these neurotransmitters are serotonin, norepinephrine, dopamine and GABA.

Alpha GPC (L-alphaglycerylphosphorylcholine): Derived originally from lecithin, Glyceryl Phosphoryl Choline is a phospholipid metabolite found concentrated in neuronal membranes. Unlike less expensive forms of choline such as choline bitrartate, Alpha GPC has been shown to be well absorbed, easily crossing the blood brain barrier. Once delivered it helps support brain function and learning processes by directly increasing the synthesis and secretion of acetylcholine. Heightened acetylcholine has been linked to memory, focus, mental drive, and REM sleep states.

Huperzia Serrata (.5% Huperzine A): An extract from the plant commonly known as Northern Firmoss (Huperzia Serrata), Huperzine A is a naturally derived acetylcholinesterase inhibitor. Acetylcholinesterase (AchE) is responsible for the breakdown of Acetylcholine, and so by inhibiting AchE, more acetylcholine is available to the brain. Efficacy has been shown in a range of 200-400 mcg daily, and safety demonstrated in trials up to 5 weeks and 600 mcg daily.

Vinpocetine: A semi-synthetic compound derived originally from the periwinkle plant, vinpocetine helps the body deliver oxygen to the brain by increasing circulation and blood flow.

AC-11: The proprietary compound licensed under agreement from Optigenex Inc, is derived from Uncaria Tomentosa, a plant indigenous to the South American rainforest. In a series of peer reviewed scientific and clinical studies conducted by third party laboratories and university medical centers, AC-11 has been shown to help the body's natural ability to repair DNA. This goes beyond other nutritional supplement by protecting the body from damage to its fundamental building blocks: The DNA itself. (Optigenex Inc is the exclusive patent holder for AC-11. US patent numbers: 6039949, 6238675 B1, 6361805 B2)

Bacopa (50% Bacosides): Bacopa Monnieri is an Ayurvedic herb found in the marshlands of India believed to help the body to enhance clear thinking. Ayurvedic masters have touted its cognitive enhancing effects for centuries. Clinical investigations show that it has strong antioxidant properties, and may protect mental function in certain adults. Bacosides, the active compounds in Bacopa, play a protective role in the synaptic functions of the nerves in the hippocampus, the seat of memory. Bacopa is believed to help the body prevent hippocampus degeneration that impairs cognition.

Pterostilbene: One of the hottest extracts in the field of nootropics, pterostilbene is quickly surpassing its cousin resveratrol in popularity. A natural antioxidant abundant in blueberries, this particular antioxidant aids in the elimination of free radicals, which are believed to contribute to ""mental fog."

L-Tyrosine: L-tyrosine is the amino acid precursor utilized by the body for the production of L-dopa. With an impeccable safety profile and a simple mechanism of action, L-tyrosine has been a highly sought after amino acid for those looking to boost brain function.

L-Theanine: L-theanine is one of the major reasons why green tea is much smoother than any other caffeinated beverage. Closely related to the GABA mechanism and easily absorbed by the body, L-theanine can help the body provide that calm sense of balance while not interfering with the stimulating buzz of activated neurotransmitters.

Oat Straw (20:1): Oat straw is one of nature's anti-stress nutrients and has been recommended for of a wide range of temporary nervous conditions. It has also been shown to help with exhaustion related neurological pains and is commonly given as a natural alternative to help combat challenges with attention span. Our formulation is extremely powerful, in a 20:1 concentration, and assists in making Alpha BRAIN a balanced nootropic.

Phosphatidylserine: Phosphatidylserine (PS) is an essential lipid compound highly abundant within brain cell membranes. Isolated from soybeans, PS supplements can help enhance mental and physical performance by mitigating stress, and boosting exercise capacity. PS is a valuable supplement for improving performance on the athletic field or on any tasks that require cognitive demand.
Boosting Neurotransmitters

The human brain is comprised of over 10 billion communicating cells, known as neurons, making over 60 trillion synaptic connections. Neurotransmitters are the chemical messengers that embody the brain’s currency of communication. The highly coordinated processes of production and release determine the relative strengths or weaknesses between neighboring neurons. These connections give rise to complex neural circuits, which underlie the apparent phenomena of human cognition.

It is well known that adequate functioning of neurotransmitter synthesis and release is essential to maintain a healthy cognitive state. Self-perceived states, such as attention, mood, focus, and awareness are highly dependent on the relative levels of neurotransmitter production. Alpha BRAIN aims to elevate the levels of the neurological production of neurotransmitters by providing an abundance of biological neurotransmitter precursors. Specifically, huperzia serrata and aGPC are targeted at increasing acetylcholine function, an essential component for learning and memory. L-theanine, a compound isolated from green tea, has been shown to mimic the important inhibitory effects of GABA neurotransmission, mediating a calm and focus mental state. L-tyrosine is a key intermediate in the biosynthesis of the neurotransmitters dopamine, epinephrine, and norepinephrine with documented mood elevating properties. Taken together, the ingredients in the Alpha BRAIN formula provide a strong foundation to enhance the body’s endogenous production and maintenance of key neurotransmitters.

Mitigating Stress

Prolonged environmental stress results in a physiological response that can be harmful to overall health and neurological function. Alpha BRAIN includes a combination of natural anti-stress compounds that have been shown to buffer the brain’s response to stress and provide an overall calming effect. Under the license from Optigenex, Alpha BRAIN is the only nootropic to include AC-11, a potent extract from Uncaria tomentosa found in the Amazon rainforest and used for hundreds of years as an alimentary herb. AC-11 has independently been proven to promote DNA repair following environmental stress and has documented cognitive benefits. Alpha BRAIN also includes highly concentrated oat straw (Avena sativa), an alleviator of exhaustion and neurological pain that has been shown to have a positive impact on cognitive performance in healthy subjects. Lastly, Alpha BRAIN contains phosphatidylserine, a phospholipid cell component known to possess ergogenic properties and promote stress tolerance in high performance athletes9. Alpha BRAIN aims to decrease our levels of endogenous stress while providing the tools to handle demanding situations, allowing a clear and focused mind.

Targeting Neurological Antioxidants

Oxidative stress, also known as free radical damage, has been implicated in a number of neurological challenges and age-related conditions. Alpha BRAIN includes the highest quality anti-oxidative compounds that have been shown to be beneficial to cognitive function. Pterostilbene, a recently discovered compound isolated from blueberries, has been shown to provide protection against free radicals. Bacopa Monnieri has been used for centuries in the traditional Ayurvedic medical system of India to improve memory and longevity, possessing both antioxidant and aptogenic effects. Research on Bacopa has shown significant memory improvements and protection again the deposit of harmful neurotoxic molecules. Finally, the inclusion of vinpocetine, a semi-synthetic derivative of the periwinkle plant, promotes blood flow to the brain and possesses potent anti-oxidant properties. These three potent antioxidants are essential to maintaining a healthy and functional nervous system.

If you want to learn more about Alpha BRAIN's mental enhancement capabilities, read some of our sources below:

  • Brancucci A: Neural correlates of cognitive ability. J Neurosci Res.
  • Crupi R, Marino A, Cuzzocrea S: New therapeutic strategy for mood disorders. Curr Med Chem, 18:4284-4298.
  • Orhan IE, Orhan G, Gurkas E: An overview on natural cholinesterase inhibitors--a multi-targeted drug class--and their mass production. Mini Rev Med Chem, 11:836-842.
  • Amenta F, Tayebati SK, Vitali D, Di Tullio MA: Association with the cholinergic precursor choline alphoscerate and the cholinesterase inhibitor rivastigmine: an approach for enhancing cholinergic neurotransmission. Mech Aging Dev 2006,127:173-179.
  • Song J, Xu H, Liu F, Feng L: Tea and cognitive health in late life: current evidence and future directions. J Nutr Health Aging, 16:31-34.
  • Mouret J, Lemoine P, Minuit MP, Robelin N: [L-tyrosine cures, immediate and long term, dopamine-dependent depressions. Clinical and polygraphic studies]. C R Acad Sci III 1988, 306:93-98.
  • Emanuel P, Scheinfeld N: A review of DNA repair and possible DNA-repair adjuvants and selected natural antioxidants. Dermatol Online J 2007, 13:10.
  • Dimpfel W, Storni C, Verbruggen M: Ingested oat herb extract (Avena sativa) changes EEG spectral frequencies in healthy subjects. J Altern Complement Med, 17:427-434.
  • Starks MA, Starks SL, Kingsley M, Purpura M, Jager R: The effects of phosphatidylserine on endocrine response to moderate intensity exercise. J Int Soc Sports Nutr 2008, 5:11.
  • Ghosh N, Ghosh R, Mandal SC: Antioxidant protection: A promising therapeutic intervention in neurodegenerative disease. Free Radic Res, 45:888-905.
  • Chang J, Rimando A, Pallas M, Camins A, Porquet D, Reeves J, Shukitt-Hale B, Smith MA, Joseph JA, Casadesus G: Low-dose pterostilbene, but not resveratrol, is a potent neuromodulator in aging and Alzheimer's disease. Neurobiol Aging.
  • Stough C, Downey LA, Lloyd J, Silber B, Redman S, Hutchison C, Wesnes K, Nathan PJ: Examining the nootropic effects of a special extract of Bacopa monniera on human cognitive functioning: 90 day double-blind placebo-controlled randomized trial. Phytother Res 2008, 22:1629-1634.
  • Shinomol GK, Bharath MM, Muralidhara: Neuromodulatory Propensity of Bacopa monnieri Leaf Extract Against 3-Nitropropionic Acid-Induced Oxidative Stress: In Vitro and In Vivo Evidences. Neurotox Res.
  • Patyar S, Prakash A, Modi M, Medhi B: Role of vinpocetine in cerebrovascular diseases. Pharmacol Rep, 63:618-628.


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